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Application of Carbon Ion and Its Sensitizing Agent in Cancer Therapy: A Systematic Review
- Source :
- Frontiers in Oncology, Vol 11 (2021), Frontiers in Oncology
- Publication Year :
- 2021
- Publisher :
- Frontiers Media SA, 2021.
-
Abstract
- Carbon ion radiation therapy (CIRT) is the most advanced radiation therapy (RT) available and offers new opportunities to improve cancer treatment and research. CIRT has a unique physical and biological advantage that allow them to kill tumor cells more accurately and intensively. So far, CIRT has been used in almost all types of malignant tumors, and showed good feasibility, safety and acceptable toxicity, indicating that CIRT has a wide range of development and application prospects. In addition, in order to improve the biological effect of CIRT, scientists are also trying to investigate related sensitizing agents to enhance the killing ability of tumor cells, which has attracted extensive attention. In this review, we tried to systematically review the rationale, advantages and problems, the clinical applications and the sensitizing agents of the CIRT. At the same time, the prospects of the CIRT in were prospected. We hope that this review will help researchers interested in CIRT, sensitizing agents, and radiotherapy to understand their magic more systematically and faster, and provide data reference and support for bioanalysis, clinical medicine, radiotherapy, heavy ion therapy, and nanoparticle diagnostics.
- Subjects :
- heavy ion radiotherapy
Cancer Research
medicine.medical_specialty
medicine.medical_treatment
Cancer therapy
Tumor cells
Biological effect
radiation therapy
03 medical and health sciences
0302 clinical medicine
medicine
Medical physics
RC254-282
sensitizing agent
030304 developmental biology
0303 health sciences
Carbon ion
business.industry
carbon therapy
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Carbon Ion Radiation Therapy
Cancer treatment
Radiation therapy
clinical application
Oncology
030220 oncology & carcinogenesis
Heavy ion therapy
Systematic Review
business
Subjects
Details
- ISSN :
- 2234943X
- Volume :
- 11
- Database :
- OpenAIRE
- Journal :
- Frontiers in Oncology
- Accession number :
- edsair.doi.dedup.....37e27119c2b390795dc4da8920ab3271