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Analytical performance of the Xpert MTB/XDR® assay for tuberculosis and expanded resistance detection
- Source :
- Diagnostic microbiology and infectious disease. 101(1)
- Publication Year :
- 2021
-
Abstract
- In a manufacturer-independent laboratory validation study, the Xpert MTB/XDR® assay demonstrated equivalent limit of detection to Xpert MTB/RIF®, detected 100% of tested resistance mutations and showed some utility for resistance detection in strain mixtures. The Xpert MTB/XDR assay is a reliable, sensitive assay for tuberculosis and expanded resistance detection.
- Subjects :
- 0301 basic medicine
Microbiology (medical)
Validation study
Tuberculosis
030106 microbiology
Microbial Sensitivity Tests
Biology
Sensitivity and Specificity
03 medical and health sciences
0302 clinical medicine
Bacterial Proteins
Drug Resistance, Bacterial
Tuberculosis, Multidrug-Resistant
medicine
030212 general & internal medicine
Antibiotics, Antitubercular
Detection limit
Drug resistant tuberculosis
General Medicine
Mycobacterium tuberculosis
respiratory system
bacterial infections and mycoses
Molecular diagnostics
medicine.disease
Virology
Infectious Diseases
Molecular Diagnostic Techniques
Mutation
Subjects
Details
- ISSN :
- 18790070
- Volume :
- 101
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Diagnostic microbiology and infectious disease
- Accession number :
- edsair.doi.dedup.....37e23f5635bb0d31ff20fe1d3ef883f7