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Trends in prescriptions for sedative–hypnotics among Korean adults: a nationwide prescription database study for 2011–2015
- Source :
- Social Psychiatry and Psychiatric Epidemiology. 54:477-484
- Publication Year :
- 2018
- Publisher :
- Springer Science and Business Media LLC, 2018.
-
Abstract
- This study investigated prescriptions for sedative–hypnotics via data obtained from the Health Insurance Review and Assessment (HIRA) service. Data on sedative–hypnotic prescriptions from the HIRA service of the Republic of Korea were analyzed from 2011 to 2015. We included prescriptions for subjects > 18 years of age from hospitals and community healthcare centers. In addition, subgroup analyses with a subsample restricted to prescriptions from patients with diagnostic codes F510 (nonorganic insomnia) or G470 (insomnia) were performed. After analyzing the number of prescriptions by individual pharmacy items, the prescription codes were grouped as: (1) benzodiazepines; (2) non-benzodiazepines, including zolpidem; (3) antidepressants; and (4) antipsychotics. We calculated the monthly percent change in the number of prescriptions by drug group using Joinpoint regression. Among the sedative–hypnotic groups, benzodiazepines were the most commonly prescribed drugs in Korea during the study period. As a single sedative–hypnotic item, zolpidem was the most frequently prescribed medication for patients with insomnia. Prescriptions for all groups of sedative–hypnotics increased significantly during the study period. When stratified by age group, antipsychotic prescriptions increased significantly by 0.19–0.21% per month among men and women aged 50–59 years and > 70 years. Prescriptions for antidepressants in 30–39-year-old men increased significantly by 0.20%. Benzodiazepine prescriptions as well as those for antipsychotics and antidepressants to treat insomnia increased during 2011–2015 in Korea. Monitoring the use of sedative–hypnotics at the national level is necessary, especially in the elderly population.
- Subjects :
- Adult
Male
medicine.medical_specialty
Zolpidem
Health (social science)
Adolescent
Databases, Factual
Social Psychology
Epidemiology
medicine.drug_class
medicine.medical_treatment
Pharmacy
Drug Prescriptions
Benzodiazepines
Young Adult
03 medical and health sciences
Age Distribution
0302 clinical medicine
Sleep Initiation and Maintenance Disorders
Republic of Korea
medicine
Insomnia
Humans
Hypnotics and Sedatives
030212 general & internal medicine
Sex Distribution
Medical prescription
Antipsychotic
Aged
Benzodiazepine
business.industry
Middle Aged
Antidepressive Agents
030227 psychiatry
Psychiatry and Mental health
Sleep Aids, Pharmaceutical
Family medicine
Female
Diagnosis code
medicine.symptom
business
Antipsychotic Agents
medicine.drug
Subjects
Details
- ISSN :
- 14339285 and 09337954
- Volume :
- 54
- Database :
- OpenAIRE
- Journal :
- Social Psychiatry and Psychiatric Epidemiology
- Accession number :
- edsair.doi.dedup.....37c022357774c90bc1a2463bd1db73cc