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Y-Chromosome Haplogroups in the Bosnian-Herzegovinian Population Based on 23 Y-STR Loci
- Source :
- Human Biology. 88:201
- Publication Year :
- 2016
- Publisher :
- Project MUSE, 2016.
-
Abstract
- In a study of the Bosnian-Herzegovinian (B&H) population, Y-chromosome marker frequencies for 100 individuals, generated using the PowerPlex Y23 kit, were used to perform Y-chromosome haplogroup assignment via Whit Athey's Haplogroup Predictor. This algorithm determines Y-chromosome haplogroups from Y-chromosome short tandem repeat (Y-STR) data using a Bayesian probability-based approach. The most frequent haplogroup appeared to be I2a, with a prevalence of 49%, followed by R1a and E1b1b, each accounting for 17% of all haplogroups within the population. Remaining haplogroups were J2a (5%), I1 (4%), R1b (4%), J2b (2%), G2a (1%), and N (1%). These results confirm previously published preliminary B&H population data published over 10 years ago, especially the prediction about the B&H population being a part of the Western Balkan area, which served as the Last Glacial Maximum refuge for the Paleolithic human European population. Furthermore, the results corroborate the hypothesis that this area was a significant stopping point on the "Middle East-Europe highway" during the Neolithic farmer migrations. Finally, since these results are almost completely in accordance with previously published data on B&H and neighboring populations generated by Y-chromosome single nucleotide polymorphism analysis, it can be concluded that in silico analysis of Y-STRs is a reliable method for approximation of the Y- chromosome haplogroup diversity of an examined population.
- Subjects :
- Genetic Markers
0301 basic medicine
bosnian-herzegovinian population
whit athey's haplogroup predictor
y chromosome
y haplogroups
y-strs
Haplogroup N
Human Migration
Population
Biology
Haplogroup NO
Haplogroup
03 medical and health sciences
Genetics
Humans
Computer Simulation
education
Genetics (clinical)
Ecology, Evolution, Behavior and Systematics
Bosnia and Herzegovina
education.field_of_study
Chromosomes, Human, Y
Haplotype
Reproducibility of Results
Bayes Theorem
Haplogroup IJ
humanities
Genetics, Population
030104 developmental biology
Haplotypes
Genealogical DNA test
Haplogroup CT
Microsatellite Repeats
Demography
Subjects
Details
- ISSN :
- 00187143
- Volume :
- 88
- Database :
- OpenAIRE
- Journal :
- Human Biology
- Accession number :
- edsair.doi.dedup.....379b5f27148c16a62173c102214d5547
- Full Text :
- https://doi.org/10.13110/humanbiology.88.3.0201