Cytokine production by peripheral blood TIM-3 positive NK and CD8+T cells during pregnancy

s / Journal of Reproductive Immunology 101–102 (2014) 40–60 43 whom markers other than interleukins were determined (n=88); first-trimester pregnant women in whom only interleukins were determined (n=80). These subgroups were subsequently divided according to the development of pregnancy in the third trimester. Each subgroup consists of an equal number of pathological and physiological pregnancies. Measured markers: Serum anti-cardiolipin autoantibodies IgG (ACLA-G) and IgM (ACLA-M), interleukins: IL-6, IL-12, IL-15, IL-16, IL-17, IL-18, and IL-23 (by a standard ELISA). Results: In group C the percentage of IL-6 (p=0.002), IL-18 (p=0.016), IL-23 (p=0.002), and ACLA-G (p