Back to Search
Start Over
Recapture of GFP chromophore fluorescence in a protein host
- Source :
- ACS combinatorial science. 13(3)
- Publication Year :
- 2011
-
Abstract
- When encapsulated by human serum albumin (HSA), certain derivatives of the green fluorescent protein (GFP) chromophore recover their fluorescence due to inhibition of torsional motion. These derivatives show remarkable sensitivity and selectivity as well as favorable spectroscopic properties toward HSA, thus providing selective probes for this and similar proteins and demonstrating the use of GFP chromophores as topological fluorophores.
- Subjects :
- Models, Molecular
Chemistry
Protein Conformation
Green Fluorescent Proteins
A protein
General Chemistry
General Medicine
Chromophore
Human serum albumin
Fluorescence
Green fluorescent protein
body regions
Spectrometry, Fluorescence
Biochemistry
embryonic structures
medicine
Humans
Selectivity
Serum Albumin
medicine.drug
Subjects
Details
- ISSN :
- 21568944
- Volume :
- 13
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- ACS combinatorial science
- Accession number :
- edsair.doi.dedup.....374642d42540d321d5da62c4c67b8b1e