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Jet-Fluid Effects on the Stented-Flow Structure in the Cavity of Cerebral Aneurysm

Authors :
Makoto Ohta
Daniel A. Rüfenacht
Miki Hirabayashi
Kazuhiro Oiwa
Bastien Chopard
Hiroaki Kojima
Source :
Biophysical Journal. 98:407a
Publication Year :
2010
Publisher :
Elsevier BV, 2010.

Abstract

The endovascular treatment of cerebral aneurysms using coils and stents, which are metal mesh cylinders, provides a promising alternative to open surgery. Although various analyses on the property of stented flow have been presented [1,2], the flow reduction mechanisms are not completely understood.Our numerical simulation indicates that the jet flow through stent struts can reduce near the aneurysm mouth but increases the flow speed far from the mouth (Fig. 1). In this work, based on this observation, we reveal the effect of the phenomenon that the pulsed jet flow drives the fluid with different velocity on the flow structure in the aneurysm cavity. As a result, we found a possibility that the shape of aneurysm may induce the self-oscillation of jet flow.We expect that our findings introduce new strategies in stent development and improve the endovascular treatment of cerebral aneurysms.[1] Biondi, A., et al., Neurosurgery, 61, 460-468 (2007)[2] Appanaboyina, S., et al., Int. J. Numer. Meth. Fluids, 57, 475-493 (2008)View Large Image | View Hi-Res Image | Download PowerPoint Slide

Details

ISSN :
00063495
Volume :
98
Database :
OpenAIRE
Journal :
Biophysical Journal
Accession number :
edsair.doi.dedup.....3743ac4523e6cccdc9870d8bef1f0bec