Supplementary Figure 5 from Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis

PDF file - 142K, MCT1 inhibition blocks glycolysis in Burkitt lymphoma cells, without affecting the steady state levels of glycolytic enzymes. Schematic of glutathione (GSH) metabolism and levels of components of glutamylcysteine ligase (GCL) in Raji BL cells treated with SR13800.