Back to Search
Start Over
Male Reproductive Health After Childhood, Adolescent, and Young Adult Cancers: A Report From the Children's Oncology Group
- Source :
- Journal of Clinical Oncology. 30:3408-3416
- Publication Year :
- 2012
- Publisher :
- American Society of Clinical Oncology (ASCO), 2012.
-
Abstract
- The majority of children, adolescents, and young adults diagnosed with cancer will become long-term survivors. Although cancer therapy is associated with many adverse effects, one of the primary concerns of young male cancer survivors is reproductive health. Future fertility is often the focus of concern; however, it must be recognized that all aspects of male health, including pubertal development, testosterone production, and sexual function, can be impaired by cancer therapy. Although pretreatment strategies to preserve reproductive health have been beneficial to some male patients, many survivors remain at risk for long-term reproductive complications. Understanding risk factors and monitoring the reproductive health of young male survivors are important aspects of follow-up care. The Children's Oncology Group Long-Term Follow-Up Guidelines for Survivors of Childhood, Adolescent, and Young Adult Cancer (COG-LTFU Guidelines) were created by the COG to provide recommendations for follow-up care of survivors at risk for long-term complications. The male health task force of the COG-LTFU Guidelines, composed of pediatric oncologists, endocrinologists, nurse practitioners, a urologist, and a radiation oncologist, is responsible for updating the COG-LTFU Guidelines every 2 years based on literature review and expert consensus. This review summarizes current task force recommendations for the assessment and management of male reproductive complications after treatment for childhood, adolescent, and young adult cancers. Issues related to male health that are being investigated, but currently not included in the COG-LTFU Guidelines, are also discussed. Ongoing investigation will inform future COG-LTFU Guideline recommendations for follow-up care to improve health and quality of life for male survivors.
- Subjects :
- Adult
Male
Oncology
Infertility
Cancer Research
medicine.medical_specialty
Adolescent
Puberty, Precocious
Review Article
Young Adult
Quality of life (healthcare)
Risk Factors
Neoplasms
Internal medicine
medicine
Humans
Testosterone
Survivors
Young adult
Child
Infertility, Male
Radiation oncologist
Reproductive health
Cryopreservation
Puberty, Delayed
business.industry
Gonadal Disorders
Guideline
medicine.disease
Sexual Dysfunction, Physiological
Reproductive Health
Sexual dysfunction
medicine.symptom
business
Sexual function
human activities
Semen Preservation
Subjects
Details
- ISSN :
- 15277755 and 0732183X
- Volume :
- 30
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Oncology
- Accession number :
- edsair.doi.dedup.....36f94d6d13d6bd412b9dcd19c9f31930