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Clinical efficacy of spleen-preserving distal pancreatectomy with or without splenic vessel preservation
- Source :
- Medicine
- Publication Year :
- 2017
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2017.
-
Abstract
- Objective: The meta-analysis was performed to investigate the clinical efficacy of spleen-preserving distal pancreatectomy with splenic vessel preservation (SPDP-SVP) and spleen-preserving distal pancreatectomy with splenic vessel resection (SPDP-SVR). Methods: Potential articles were searched on the databases of Pubmed, Embase, and Chinese National Knowledge Infrastructure (CNKI) from January 1988 until March 2017. Weight mean difference (WMD) with 95% confidence interval (CI) was applied to compare the efficacy of SPDP-SVP and SPDP-SVR. Odds ratio (OR) with 95% CI was calculated to figure out the risks for complications. P50% indicated significant heterogeneity. The random-effects model is used to pool data if significant heterogeneity exists; otherwise, the fixed-effects model is used. Publication bias was evaluated by Begg's funnel plot. Results: Thirteen eligible articles were obtained in the meta-analysis. SPDP-SVP seemed to relate with reduced operative time and blood loss, prolonged hospital stay, and less complications; however, the effects were not statistically significant. Meanwhile, we found that SPDP-SVP was closely related with the reduced rate of splenic infarction and gastric varices (OR = 0.16, 95% CI = 0.09–0.29; OR = 0.08, 95% CI = 0.02–0.35). No publication bias was observed in the analysis (P = .636). Conclusions: SPDP-SVP seems to show superiority than SPDP-SVR in reducing the rate of splenic infarction and gastric varices.
- Subjects :
- medicine.medical_specialty
Funnel plot
medicine.medical_treatment
Operative Time
Blood Loss, Surgical
Infarction
splenic vessel preservation
Gastroenterology
Varicose Veins
03 medical and health sciences
Pancreatectomy
Postoperative Complications
0302 clinical medicine
splenic vessel resection
Internal medicine
medicine
Humans
business.industry
General Medicine
Publication bias
Odds ratio
Length of Stay
Gastric varices
medicine.disease
Confidence interval
Surgery
meta-analysis
030220 oncology & carcinogenesis
Splenic infarction
030211 gastroenterology & hepatology
business
Spleen
Systematic Review and Meta-Analysis
Research Article
Subjects
Details
- ISSN :
- 00257974
- Volume :
- 96
- Database :
- OpenAIRE
- Journal :
- Medicine
- Accession number :
- edsair.doi.dedup.....36f69e9cb15888d35ac5fb8e0fbfaba2