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Thyrotropin releasing hormone: Antagonism of pentobarbital in rodents
- Source :
- Life Sciences. 14:447-455
- Publication Year :
- 1974
- Publisher :
- Elsevier BV, 1974.
-
Abstract
- Thyrotropin releasing hormone (TRH) antagonizes the behavioral and temperature reducing effects of pentobarbital in rodents. The hormone is effective whether given before or after the barbiturate. This antagonism by TRH of the effects of pentobarbital probably does not depend upon thyroid hormone release as L-triiodothyronine administration is ineffective.
- Subjects :
- Male
endocrine system
medicine.medical_specialty
Pentobarbital
Time Factors
endocrine system diseases
medicine.drug_class
Thyrotropin-releasing hormone
General Biochemistry, Genetics and Molecular Biology
Body Temperature
Mice
Internal medicine
medicine
Animals
General Pharmacology, Toxicology and Pharmaceutics
Thyrotropin-Releasing Hormone
Behavior, Animal
business.industry
Thyroid
General Medicine
Hormone release
Endocrinology
medicine.anatomical_structure
Barbiturate
Triiodothyronine
business
Antagonism
Drug Antagonism
hormones, hormone substitutes, and hormone antagonists
medicine.drug
Hormone
Subjects
Details
- ISSN :
- 00243205
- Volume :
- 14
- Database :
- OpenAIRE
- Journal :
- Life Sciences
- Accession number :
- edsair.doi.dedup.....36deaae4e014c861f02bdd25f2059ece
- Full Text :
- https://doi.org/10.1016/0024-3205(74)90359-2