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Sublethal infection of C57BL/6 mice with Salmonella enterica Serovar Typhimurium leads to an increase in levels of Toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs
- Source :
- Tötemeyer, S, Kaiser, P, Maskell, D J & Bryant, C E 2005, ' Sublethal infection of C57BL/6 mice with Salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs ', Infection and Immunity, vol. 73, no. 3, pp. 1873-1878 . https://doi.org/10.1128/IAI.73.3.1873-1878.2005
- Publication Year :
- 2005
-
Abstract
- Sublethal infection of C57BL/6 mice with Salmonella enterica serovar Typhimurium M525P initiates a strong inflammatory response. We measured organ expression of mRNA for Toll-like receptors and their associated signaling molecules during S. enterica serovar Typhimurium infection. During infection, the Toll-lie receptor 1 (TLR1), TLR2, and TLR9 mRNA levels increased, while TLR6 mRNA expression decreased.
- Subjects :
- Salmonella typhimurium
Immunology
Down-Regulation
Receptors, Cell Surface
Microbiology
Mice
Downregulation and upregulation
Animals
Receptor
Toll-like receptor
Messenger RNA
Mice, Inbred C3H
Salmonella Infections, Animal
Host Response and Inflammation
Membrane Glycoproteins
biology
Toll-Like Receptors
TLR9
biology.organism_classification
Toll-Like Receptor 1
Toll-Like Receptor 2
Up-Regulation
DNA-Binding Proteins
Mice, Inbred C57BL
TLR2
Infectious Diseases
Toll-Like Receptor 6
Salmonella enterica
Organ Specificity
TLR6
Toll-Like Receptor 9
Parasitology
Subjects
Details
- ISSN :
- 00199567
- Volume :
- 73
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Infection and immunity
- Accession number :
- edsair.doi.dedup.....36de4bfd6faa4ea061116e464bdf62cf