Back to Search Start Over

Sublethal infection of C57BL/6 mice with Salmonella enterica Serovar Typhimurium leads to an increase in levels of Toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs

Authors :
Peter K. Kaiser
Duncan J. Maskell
Clare E. Bryant
Sabine Tötemeyer
Source :
Tötemeyer, S, Kaiser, P, Maskell, D J & Bryant, C E 2005, ' Sublethal infection of C57BL/6 mice with Salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs ', Infection and Immunity, vol. 73, no. 3, pp. 1873-1878 . https://doi.org/10.1128/IAI.73.3.1873-1878.2005
Publication Year :
2005

Abstract

Sublethal infection of C57BL/6 mice with Salmonella enterica serovar Typhimurium M525P initiates a strong inflammatory response. We measured organ expression of mRNA for Toll-like receptors and their associated signaling molecules during S. enterica serovar Typhimurium infection. During infection, the Toll-lie receptor 1 (TLR1), TLR2, and TLR9 mRNA levels increased, while TLR6 mRNA expression decreased.

Details

ISSN :
00199567
Volume :
73
Issue :
3
Database :
OpenAIRE
Journal :
Infection and immunity
Accession number :
edsair.doi.dedup.....36de4bfd6faa4ea061116e464bdf62cf