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Detection of Bocavirus in Children Suffering from Acute Respiratory Tract Infections in Saudi Arabia
- Source :
- PLoS ONE, PLoS ONE, Vol 8, Iss 1, p e55500 (2013)
- Publication Year :
- 2013
- Publisher :
- Public Library of Science, 2013.
-
Abstract
- Human bocavirus (HBoV) was recently discovered in children with respiratory distress and/or diarrhea. To our knowledge, no previous study has reported the existence of bocavirus in Saudi Arabia. Swabs samples from 80 children with respiratory tract infections were examined for the presence of HBoV. Real-time polymerase chain reaction was used as a sensitive method to detect the HBoV. Direct gene sequencing was used to determine the genotype of the detected virus isolates. HBoV was detected in 22.5% of the examined patients. The NP1 partial gene sequence from all patients showed that the circulated strains were related to HBoV-1 genotype. Most of HBoV infected patients showed evidence of mixed coinfection with other viral pathogens. The current study clearly demonstrated that genetically conserved HBoV1 circulates in Saudi Arabia. Interestingly, most of the HBoV1 infected cases were associated with high rates of co-infections with other viruses.
- Subjects :
- Male
Viral Diseases
Epidemiology
lcsh:Medicine
law.invention
law
Human bocavirus
Genotype
Prevalence
Clinical Epidemiology
lcsh:Science
Pediatric Epidemiology
Child
Respiratory Tract Infections
Polymerase chain reaction
Phylogeny
Multidisciplinary
biology
Respiratory tract infections
Respiratory distress
General Medicine
Human Bocavirus Infection
Clinical Laboratory Sciences
Diarrhea
Infectious Diseases
Child, Preschool
Coinfection
Medicine
Female
medicine.symptom
General Agricultural and Biological Sciences
Research Article
Molecular Sequence Data
Saudi Arabia
Microbiology
General Biochemistry, Genetics and Molecular Biology
Virus
Infectious Disease Epidemiology
Parvoviridae Infections
Viral Proteins
Diagnostic Medicine
Virology
medicine
Humans
Biology
lcsh:R
Infant, Newborn
Infant
biology.organism_classification
medicine.disease
Viral Disease Diagnosis
Emerging Infectious Diseases
lcsh:Q
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 8
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....36cf4725ccdaf755f4e09e4f5754b577