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Nicotinic and muscarinic reactive sites in mammalian glomus cells
- Source :
- Brain research. 252(1)
- Publication Year :
- 1982
-
Abstract
- Nicotinic and muscarinic sites on glomus cell membranes of cats, rabbits and mice were determined in carotid body slices. Cells were impaled under Nomarski optics. Resting potentials were 11.1-73.1 mV and input resistances were 11-250 M omega. Nicotine, pilocarpine or bethanechol depolarized glomus cells and their input resistance decreased. Curare or alpha-bungarotoxin reduced nicotine effects. Atropine had similar effects on the responses to pilocarpine or bethanechol.
- Subjects :
- medicine.medical_specialty
Bethanechol
Receptors, Nicotinic
Synaptic Transmission
Membrane Potentials
Mice
Glomus cell
Internal medicine
Muscarinic acetylcholine receptor
medicine
Animals
Receptors, Cholinergic
Molecular Biology
Neurons
Carotid Body
Chemistry
General Neuroscience
fungi
Receptors, Muscarinic
Acetylcholine
Curare
Atropine
medicine.anatomical_structure
Endocrinology
Nicotinic agonist
Pilocarpine
Cats
Carotid body
Neurology (clinical)
Rabbits
Developmental Biology
medicine.drug
Subjects
Details
- ISSN :
- 00068993
- Volume :
- 252
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Brain research
- Accession number :
- edsair.doi.dedup.....36b5cf6628fc92ae78e5a0412a718c3e