Back to Search
Start Over
Associations between the size and location of myocardial infarction and cerebral infarction
- Source :
- Journal of the Neurological Sciences. 419:117182
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- Background Myocardial infarction (MI) is a known cause of cerebral infarction. We assessed whether the size and location of MI is associated with the risk of cerebral infarction. Methods and results We performed a cross-sectional study of adults who underwent both brain MRI and delayed-enhancement cardiac MRI (DE-CMR) within 365 days of each other at Weill Cornell Medicine between 2014 and 2017 and had evidence of MI on DE-CMR. We used multiple logistic regression to evaluate associations between MI size and any cerebral infarction, apical MI location and any cerebral infarction, and MI size/location and cortical versus subcortical cerebral infarction. Models were adjusted for demographics, and the total number of vascular risk factors. Among 234 patients who underwent both DE-CMR and brain MRI within 365 days, 76 had evidence for MI on DE-CMR. Among these 76 patients, 51 (67.1%) had evidence of cerebral infarction. The size of MI (global MI burden) was not associated with any cerebral infarction (OR per 5% increase in MI size, 1.12; 95% CI, 0.85–1.47), but was associated with cortical cerebral infarction (OR per 5% increase in MI size, 1.30; 95% CI, 1.00.-1.68). Similarly, apical MI location was not associated with any cerebral infarction (OR 2.63, 95% CI, 0.78–8.87), but was associated with cortical cerebral infarction (OR, 3.67; 95% CI, 1.19–11.33). Conclusion Among patients with MI on cardiac MRI, both size and apical location of MI were associated with cortical cerebral infarction. Our results may help stratify cardioembolic risk and inform antithrombotic treatment algorithms among patients with MI.
- Subjects :
- Adult
medicine.medical_specialty
Demographics
Myocardial Infarction
Vascular risk
Logistic regression
03 medical and health sciences
Antithrombotic treatment
0302 clinical medicine
Predictive Value of Tests
Internal medicine
medicine
Brain mri
Humans
cardiovascular diseases
030212 general & internal medicine
Myocardial infarction
Cerebral infarction
business.industry
Cerebral Infarction
medicine.disease
Magnetic Resonance Imaging
Cross-Sectional Studies
Neurology
cardiovascular system
Cardiology
Neurology (clinical)
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 0022510X
- Volume :
- 419
- Database :
- OpenAIRE
- Journal :
- Journal of the Neurological Sciences
- Accession number :
- edsair.doi.dedup.....36810503e286de436bb630c9eeb29e66