Bio-polymeric transferrin-targeted temozolomide nanoparticles in gel for synergistic post-surgical GBM therapy

Authors :: Puja Sandbhor
Jayant. S. Goda
Bhabani Mohanty
Pradip Chaudhari
Shilpee Dutt
Rinti Banerjee
Source :: Nanoscale. 14:12773-12788
Publication Year :: 2022
Publisher :: Royal Society of Chemistry (RSC), 2022.
Abstract: Spatiotemporal targeting of anti-glioma drugs remains a pressing issue in glioblastoma (GBM) treatment. We challenge this issue by developing a minimally invasive

Subjects :: Brain Neoplasms
Polymers
Phosphorylcholine
Transferrin
Hydrogels
Glioma
Xenograft Model Antitumor Assays
Mice
Cell Line, Tumor
Delayed-Action Preparations
Temozolomide
Animals
Nanoparticles
General Materials Science
Glioblastoma

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