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A Case of Graves’ Disease Accompanied with Acute Hepatitis A Virus Infection
- Source :
- The Korean Journal of Gastroenterology, Vol 71, Iss 6, Pp 354-358 (2018)
- Publication Year :
- 2018
- Publisher :
- Jin Publishing & Printing Co., 2018.
-
Abstract
- Concurrent presentation of acute hepatitis A virus (HAV) infection and Graves' disease has not been reported in literature worldwide. Although there is no well-established mechanism that explains the induction of Graves' disease by HAV to date, our case suggests that HAV infection may be responsible for inducing Graves' disease. A healthy 27-year-old female presented fever, palpitation, and diarrhea, and she was subsequently diagnosed as acute HAV infection. Concurrently, she showed hyperthyroidism, and the diagnosis was made as Graves' disease. She had never had symptoms that suggested hyperthyroidism, and previous thyroid function test was normal. Acute HAV infection was recovered by conservative management, however, thyroid dysfunction was maintained even after normalization of liver enzymes. Methimazole was used to treat Graves' disease. We report a case of concurrent acute HAV infection and Graves' disease in a patient without preexisting thyroid disease. This suggests that HAV infection may be a trigger for an autoimmune thyroid disease in susceptible individuals.
- Subjects :
- Triggering factor
endocrine system
endocrine system diseases
medicine.medical_treatment
Graves' disease
viruses
lcsh:Medicine
030209 endocrinology & metabolism
Disease
Thyroid function tests
Virus
03 medical and health sciences
0302 clinical medicine
030225 pediatrics
medicine
medicine.diagnostic_test
business.industry
Thyroid disease
Antithyroid agent
lcsh:R
Hepatitis A
virus diseases
General Medicine
medicine.disease
digestive system diseases
Diarrhea
Immunology
Graves disease
Hepatitis A virus
medicine.symptom
business
Subjects
Details
- Language :
- English
- ISSN :
- 15989992
- Volume :
- 71
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- The Korean Journal of Gastroenterology
- Accession number :
- edsair.doi.dedup.....3659e60eedfc2bd1a359e39d3bfbe059