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Wright-Fisher construction of the two-parameter Poisson-Dirichlet diffusion
- Source :
- Ann. Appl. Probab. 27, no. 3 (2017), 1923-1950
- Publication Year :
- 2017
- Publisher :
- Institute of Mathematical Statistics, 2017.
-
Abstract
- The two-parameter Poisson--Dirichlet diffusion, introduced in 2009 by Petrov, extends the infinitely-many-neutral-alleles diffusion model, related to Kingman's one-parameter Poisson--Dirichlet distribution and to certain Fleming--Viot processes. The additional parameter has been shown to regulate the clustering structure of the population, but is yet to be fully understood in the way it governs the reproductive process. Here we shed some light on these dynamics by formulating a $K$-allele Wright--Fisher model for a population of size $N$, involving a uniform mutation pattern and a specific state-dependent migration mechanism. Suitably scaled, this process converges in distribution to a $K$-dimensional diffusion process as $N\to\infty$. Moreover, the descending order statistics of the $K$-dimensional diffusion converge in distribution to the two-parameter Poisson--Dirichlet diffusion as $K\to\infty$. The choice of the migration mechanism depends on a delicate balance between reinforcement and redistributive effects. The proof of convergence to the infinite-dimensional diffusion is nontrivial because the generators do not converge on a core. Our strategy for overcoming this complication is to prove \textit{a priori} that in the limit there is no "loss of mass", i.e., that, for each limit point of the sequence of finite-dimensional diffusions (after a reordering of components by size), allele frequencies sum to one.<br />Comment: To appear in The Annals of Applied Probability
- Subjects :
- Statistics and Probability
Two-parameter Poisson-Dirichlet distribution
Population
Mathematics - Statistics Theory
Statistics Theory (math.ST)
92D25
Infinite-dimensional diffusion process
01 natural sciences
Wright–Fisher model
Dirichlet distribution
010104 statistics & probability
symbols.namesake
FOS: Mathematics
Applied mathematics
Quantitative Biology::Populations and Evolution
Limit (mathematics)
0101 mathematics
Diffusion (business)
Quantitative Biology - Populations and Evolution
education
QA
Weak convergence
Migration
60J60
Mathematics
education.field_of_study
Reinforcement
Wright-Fisher model
Statistics, Probability and Uncertainty
Statistics
Probability (math.PR)
010102 general mathematics
Order statistic
Populations and Evolution (q-bio.PE)
two-parameter Poisson–Dirichlet distribution
Diffusion process
60F17
FOS: Biological sciences
Limit point
symbols
60G57
Probability and Uncertainty
Mathematics - Probability
Subjects
Details
- Language :
- English
- ISSN :
- 10505164
- Database :
- OpenAIRE
- Journal :
- Ann. Appl. Probab. 27, no. 3 (2017), 1923-1950
- Accession number :
- edsair.doi.dedup.....36565551d695fe8b8bf9085751b7ebf9