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Recent Advances in ROS-Responsive Cell Sheet Techniques for Tissue Engineering
- Source :
- International Journal of Molecular Sciences
- Publication Year :
- 2019
-
Abstract
- Cell sheet engineering has evolved rapidly in recent years as a new approach for cell-based therapy. Cell sheet harvest technology is important for producing viable, transplantable cell sheets and applying them to tissue engineering. To date, most cell sheet studies use thermo-responsive systems to detach cell sheets. However, other approaches have been reported. This review provides the progress in cell sheet detachment techniques, particularly reactive oxygen species (ROS)-responsive strategies. Therefore, we present a comprehensive introduction to ROS, their application in regenerative medicine, and considerations on how to use ROS in cell detachment. The review also discusses current limitations and challenges for clarifying the mechanism of the ROS-responsive cell sheet detachment.
- Subjects :
- 0301 basic medicine
Cell
cell sheet
02 engineering and technology
Review
Regenerative medicine
Catalysis
Inorganic Chemistry
03 medical and health sciences
Tissue engineering
medicine
Animals
Humans
Physical and Theoretical Chemistry
Molecular Biology
Spectroscopy
Cell sheet
chemistry.chemical_classification
reactive oxygen species
Reactive oxygen species
Tissue Engineering
Mechanism (biology)
Organic Chemistry
General Medicine
021001 nanoscience & nanotechnology
cell detachment
Ros responsive
Computer Science Applications
Cell biology
030104 developmental biology
medicine.anatomical_structure
chemistry
0210 nano-technology
Subjects
Details
- ISSN :
- 14220067
- Volume :
- 20
- Issue :
- 22
- Database :
- OpenAIRE
- Journal :
- International journal of molecular sciences
- Accession number :
- edsair.doi.dedup.....36495ba716cc7cc2d37264dfb38d0280