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Simultaneous Lactate Editing and Observation of Other Metabolites Using a Stimulated-Echo-Enhanced Double-Quantum Filter
- Source :
- Journal of Magnetic Resonance. 137:215-220
- Publication Year :
- 1999
- Publisher :
- Elsevier BV, 1999.
-
Abstract
- Conventional double-quantum editing techniques recover only one metabolite at a time, and are thus inefficient for monitoring metabolic changes involving several metabolites. In this paper, a stimulated-echo-enhanced selective double-quantum coherence transfer (STE-SelDQC) sequence is described, which allows simultaneous observation of lactate and other metabolites in a single scan while leaving fat and water signals suppressed. A frequency selective double-quantum filter designed for lactate editing suppresses fat and water resonances and a stimulated-echo window of adjustable frequency and bandwidth is incorporated into the double-quantum filter for simultaneous observation of other metabolites. The performance of the sequence is demonstrated in phantoms and rat brain tissue.
- Subjects :
- Nuclear and High Energy Physics
Echo-Planar Imaging
Phantoms, Imaging
Metabolite
Bandwidth (signal processing)
Biophysics
Brain
Models, Theoretical
Creatine
equipment and supplies
Condensed Matter Physics
Rat brain
Biochemistry
Choline
Rats
chemistry.chemical_compound
Nuclear magnetic resonance
Body Water
chemistry
Animals
Lactic Acid
Single scan
Stimulated echo
Double quantum
gamma-Aminobutyric Acid
Subjects
Details
- ISSN :
- 10907807
- Volume :
- 137
- Database :
- OpenAIRE
- Journal :
- Journal of Magnetic Resonance
- Accession number :
- edsair.doi.dedup.....3620eee8650026058513e118b2c097a1