A New Iodinated Metabolite and a New Alkyl Sulfate from the Senegalese Sponge Ptilocaulis spiculifer

The hydrophilic extract of the Senegalese sponge Ptilocaulis spiculifer has been analyzed. It has been shown to contain dakaramine (1), a new tyrosine derivative containing iodine, an unusual feature for sponge metabolites. In addition, the new alkyl sulfate 2 (as a counterion of 1) and the known ecdysonic sterol 3 were isolated from the same extract.