Tumor microenvironment-responsive S-NSs-TPZ-ICG intelligent nanoplatforms for synergistically enhanced tumor multimodal therapy

Authors :: Xiangcao Li
Shaojing Zhao
Ke Yang
Baoling Li
Benhua Wang
Jianing Yi
Xiangzhi Song
Minhuan Lan
Source :: Chemical Communications. 58:6251-6254
Publication Year :: 2022
Publisher :: Royal Society of Chemistry (RSC), 2022.
Abstract: Nanosheet carriers loaded with drugs and phototherapeutics are used for effective cancer therapy, but the process remains challenging. Here, we prepared sulfur nanosheets (S-NSs) and then loaded tirapazamine (TPZ) and indocyanine green (ICG) with a loading efficiency of 6.3% and 94%, respectively. The obtained S-NSs-TPZ-ICG exhibits near-infrared (NIR) fluorescence, high

Subjects :: Indocyanine Green
Metals and Alloys
Hydrogen Peroxide
General Chemistry
Phototherapy
Catalysis
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Cell Line, Tumor
Neoplasms
Tumor Microenvironment
Materials Chemistry
Ceramics and Composites
Humans
Nanoparticles
Tirapazamine
Sulfur

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