Back to Search
Start Over
A Case of Generalized Lichen Sclerosus et Atrophicus
- Source :
- Annals of Dermatology
- Publication Year :
- 2020
- Publisher :
- The Korean Dermatological Association; The Korean Society for Investigative Dermatology, 2020.
-
Abstract
- A 62-year-old female, with previous history of asthma and hypertension, presented with generalized hyperpigmented skin lesion, found a year ago. Physical examination revealed brown colored lichenified and sclerotic patches on the lower abdomen and flexural areas of extremities. Punch biopsy was performed and histopathological examination revealed hyperkeratosis, follicular plugging and thinning in epidermis. In dermoepidermal junction, cleft like space separating atrophic epidermis and dermis was seen. Also, lichenoid lymphocytic infiltration was observed in mid-dermis. Based on clinical and histopathological findings, a diagnosis of generlaized lichen sclerosus et atrophicus (LSA) was made. Other laboratory examinations were unremarkable. As there is no standard treatment for LSA, the patient received various treatments including topical steroid, tacrolimus and narrow- band ultraviolet B therapy. The skin lesion has softened and its color improved after treatment. LSA is defined as infrequent chronic inflammatory dermatosis with anogenital and extragenital manifestations. Generalized type is rare and genital involvement is the most frequent and often the only site of involvement. We report this case as it is an uncommon type of LSA with generalized hyperpigmented and sclerotic skin lesion in a postmenopausal female patient. (Ann Dermatol 32(4) 327∼330, 2020)
- Subjects :
- medicine.medical_specialty
medicine.medical_treatment
Hyperkeratosis
Physical examination
Case Report
Dermatology
Lichen sclerosus
Lesion
030207 dermatology & venereal diseases
03 medical and health sciences
0302 clinical medicine
Dermis
Lichen sclerosus et atrophicus
Medicine
Dermoepidermal junction
medicine.diagnostic_test
business.industry
Generalized
medicine.disease
medicine.anatomical_structure
030220 oncology & carcinogenesis
Abdomen
medicine.symptom
business
Topical steroid
Subjects
Details
- Language :
- English
- ISSN :
- 20053894 and 10139087
- Volume :
- 32
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Annals of Dermatology
- Accession number :
- edsair.doi.dedup.....35d091a6c67ca476f309fc680830582d