Back to Search
Start Over
Effect of Cardiovascular and Metabolic Disease on Cognitive Test Performance and Cognitive Change in Older Adults
- Source :
- Journal of the American Geriatrics Society 60(7), 1286-1291 (2012). doi:10.1111/j.1532-5415.2012.04032.x, Journal of the American Geriatrics Society, Vol. 60, No 7 (2012) pp. 1286-1291
- Publication Year :
- 2012
- Publisher :
- Wiley, 2012.
-
Abstract
- Objectives: To examine the effect of cardiovascular and metabolic diseases on initial cognitive test performance and rate of change in three cognitive measures. Design: Prospective cohort study. Setting: General practices in six towns throughout Germany. Participants: Three thousand three hundred twenty-seven participants aged 75 and older (average 79.7 ± 3.6). Measurements: Data were collected during home visits every 18 months and included sociodemographic variables, depression, disease status, drug intake, and cognition. Results: Although the presence of transient ischemic attack (TIA) or stroke and diabetes mellitus was related to poor initial cognitive test performance, the presence of those and other far-reaching chronic diseases or a higher disease burden were not related to the rate of change in cognition over time. Conclusion: Diabetes mellitus, stroke and TIA affect cognitive test performance beyond well-known sociodemographic variables and depressive symptoms, although none of these diseases contributed to cognitive decline over time. In practical terms, prevention and diagnosis of cardiovascular and metabolic diseases may be essential to cognitively healthy aging.
- Subjects :
- Male
Gerontology
complications [Cardiovascular Diseases]
physiopathology [Depression]
Interviews as Topic
ddc:150
Germany
Diabetes mellitus
complications [Depression]
Diabetes Mellitus
medicine
Humans
ddc:610
Longitudinal Studies
Prospective Studies
Cognitive decline
Prospective cohort study
Stroke
Depression (differential diagnoses)
Disease burden
Aged
Aged, 80 and over
Psychiatric Status Rating Scales
Depression
business.industry
etiology [Cognition Disorders]
physiopathology [Cardiovascular Diseases]
Cognition
medicine.disease
Cognitive test
Cardiovascular Diseases
physiopathology [Cognition Disorders]
Female
Geriatrics and Gerontology
Cognition Disorders
business
physiopathology [Diabetes Mellitus]
Subjects
Details
- ISSN :
- 00028614
- Volume :
- 60
- Database :
- OpenAIRE
- Journal :
- Journal of the American Geriatrics Society
- Accession number :
- edsair.doi.dedup.....35cd215780e8c7b3953deb6574342640