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Comprehensive Versus Usual Community Care for First-Episode Psychosis: 2-Year Outcomes From the NIMH RAISE Early Treatment Program
- Source :
- American Journal of Psychiatry. 173:362-372
- Publication Year :
- 2016
- Publisher :
- American Psychiatric Association Publishing, 2016.
-
Abstract
- Objective:The primary aim of this study was to compare the impact of NAVIGATE, a comprehensive, multidisciplinary, team-based treatment approach for first-episode psychosis designed for implementation in the U.S. health care system, with community care on quality of life.Method:Thirty-four clinics in 21 states were randomly assigned to NAVIGATE or community care. Diagnosis, duration of untreated psychosis, and clinical outcomes were assessed via live, two-way video by remote, centralized raters masked to study design and treatment. Participants (mean age, 23) with schizophrenia and related disorders and ≤6 months of antipsychotic treatment (N=404) were enrolled and followed for ≥2 years. The primary outcome was the total score of the Heinrichs-Carpenter Quality of Life Scale, a measure that includes sense of purpose, motivation, emotional and social interactions, role functioning, and engagement in regular activities.Results:The 223 recipients of NAVIGATE remained in treatment longer, experienced greater ...
- Subjects :
- medicine.medical_specialty
Psychosis
business.industry
MEDLINE
medicine.disease
030227 psychiatry
law.invention
03 medical and health sciences
Psychiatry and Mental health
0302 clinical medicine
Quality of life (healthcare)
Randomized controlled trial
Multidisciplinary approach
Schizophrenia
law
Health care
medicine
InformationSystems_MISCELLANEOUS
Young adult
business
Psychiatry
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 15357228 and 0002953X
- Volume :
- 173
- Database :
- OpenAIRE
- Journal :
- American Journal of Psychiatry
- Accession number :
- edsair.doi.dedup.....35922a8255372adc15d3c2b0f7895f6b