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Ten-Year Probabilities of Death Due to Cancer and Cardiovascular Disease among Breast Cancer Patients Diagnosed in North-Eastern Spain
- Source :
- International Journal of Environmental Research and Public Health; Volume 20; Issue 1; Pages: 405
- Publication Year :
- 2022
- Publisher :
- MDPI AG, 2022.
-
Abstract
- Mortality from cardiovascular disease (CVD), second tumours, and other causes is of clinical interest in the long-term follow-up of breast cancer (BC) patients. Using a cohort of BC patients (N = 6758) from the cancer registries of Girona and Tarragona (north-eastern Spain), we studied the 10-year probabilities of death due to BC, other cancers, and CVD according to stage at diagnosis and hormone receptor (HR) status. Among the non-BC causes of death (N = 720), CVD (N = 218) surpassed other cancers (N = 196). The BC cohort presented a significantly higher risk of death due to endometrial and ovarian cancers than the general population. In Stage I, HR− patients showed a 1.72-fold higher probability of all-cause death and a 6.11-fold higher probability of breast cancer death than HR+ patients. In Stages II–III, the probability of CVD death (range 3.11% to 3.86%) surpassed that of other cancers (range 0.54% to 3.11%). In Stage IV patients, the probability of death from any cancer drove the mortality risk. Promoting screening and preventive measures in BC patients are warranted, since long-term control should encompass early detection of second neoplasms, ruling out the possibility of late recurrence. In patients diagnosed in Stages II–III at an older age, surveillance for preventing late cardiotoxicity is crucial.
- Subjects :
- Breast cancer
Cardiovascular diseases
Malalties cardiovasculars
Health, Toxicology and Mutagenesis
breast cancer
probability of death
cardiovascular disease
second tumours
causes of death
stage
hormone receptor status
Mortalitat
Public Health, Environmental and Occupational Health
Mortality
Càncer de mama
Subjects
Details
- ISSN :
- 16604601
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- International Journal of Environmental Research and Public Health
- Accession number :
- edsair.doi.dedup.....353ed0bd28cae8757e460934f366bc61