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Tissue-Resident Innate and Innate-Like Lymphocyte Responses to Viral Infection
- Source :
- Viruses, vol 11, iss 3, Viruses, Viruses, Vol 11, Iss 3, p 272 (2019)
- Publication Year :
- 2019
- Publisher :
- eScholarship, University of California, 2019.
-
Abstract
- Infection is restrained by the concerted activation of tissue-resident and circulating immune cells. Recent discoveries have demonstrated that tissue-resident lymphocyte subsets, comprised of innate lymphoid cells (ILCs) and unconventional T cells, have vital roles in the initiation of primary antiviral responses. Via direct and indirect mechanisms, ILCs and unconventional T cell subsets play a critical role in the ability of the immune system to mount an effective antiviral response through potent early cytokine production. In this review, we will summarize the current knowledge of tissue-resident lymphocytes during initial viral infection and evaluate their redundant or nonredundant contributions to host protection or virus-induced pathology.
- Subjects :
- 0301 basic medicine
Lymphocyte
medicine.medical_treatment
lcsh:QR1-502
Review
Viral infection
lcsh:Microbiology
Mice
0302 clinical medicine
T-Lymphocyte Subsets
2.1 Biological and endogenous factors
Innate
Aetiology
tissue resident
Clinical Trials as Topic
Innate lymphoid cell
Cell Differentiation
3. Good health
Infectious Diseases
medicine.anatomical_structure
Cytokine
Virus Diseases
innate lymphoid cell
HIV/AIDS
Infection
Lymphocyte subsets
Lymphoid Tissue
1.1 Normal biological development and functioning
T cell
Biology
Microbiology
Vaccine Related
03 medical and health sciences
Immune system
Underpinning research
Virology
unconventional T cell
medicine
Animals
Humans
Animal
Inflammatory and immune system
Immunity
Immunity, Innate
Disease Models, Animal
030104 developmental biology
Immunology
Disease Models
viral infection
030215 immunology
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- Viruses, vol 11, iss 3, Viruses, Viruses, Vol 11, Iss 3, p 272 (2019)
- Accession number :
- edsair.doi.dedup.....353353c8f6501ce924f61853c3db21a9