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Effects of antibiotic consumption on children 2-8 years of age developing asthma

Authors :
Javad Khashabi
Sima Oshnouei
M Karamyar
Mohammadhossein Rahimi Rad
Hamid Reza Khalkhali
Shaker Salarilak
Source :
Epidemiology and Health, Vol 36 (2014), Epidemiology and Health
Publication Year :
2014
Publisher :
Korean Society of Epidemiology, 2014.

Abstract

OBJECTIVES Antibiotic exposure in children is a possible contributor to the increasing asthma prevalence in several countries. The present study aimed to investigate the association between antibiotic exposure and the risk of developing childhood asthma at 2-8 years of age. METHODS A case-control study was undertaken among children aged 2-8 years old between March and September 2010 in the Urmia district in the northwest of Iran. The cases were doctor-diagnosed asthmatic children based on Global Initiative for Asthma criteria (n=207), and the controls were children without respiratory symptoms (n=400) selected by frequency matching by age and gender. Clinical data including antibiotic exposure was collected by a validated and reliable questionnaire, which was completed by interviewing parents/guardians. RESULTS Antibiotic consumption during the first year of life increased the odds ratio [OR] of asthma symptoms at 2-8 years of age (crude OR, 2.26; 95% confidence interval [CI], 1.53-3.35; p

Details

ISSN :
20927193
Volume :
36
Database :
OpenAIRE
Journal :
Epidemiology and Health
Accession number :
edsair.doi.dedup.....34f614dcfb68d9875cf6b3e840a8cc2f
Full Text :
https://doi.org/10.4178/epih/e2014006