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Nucleotide sequence of the gyrA gene of Arcobacter species and characterization of human ciprofloxacin-resistant clinical isolates
- Source :
- FEMS Immunology & Medical Microbiology, FEMS Immunology & Medical Microbiology, 2007, 49 (3), pp.337-45. ⟨10.1111/j.1574-695X.2006.00208.x⟩
- Publication Year :
- 2007
- Publisher :
- HAL CCSD, 2007.
-
Abstract
- International audience; The nucleotide sequence of the gyrA gene of Arcobacter butzleri, Arcobacter cryaerophilus, Arcobacter cibarius, and Arcobacter skirrowii was determined. The deduced GyrA proteins are closely related to those of Wolinella succinogenes and Helicobacter pullorum, whereas those of Campylobacter species showed less sequence identity. The phylogenetic analysis of GyrA sequences provides a result similar to 16S rRNA gene sequence phylogenetic analysis and allows the discrimination among A. butzleri species. In addition, a Thr-->Ile mutation at amino acid 85 in the quinolone resistance-determining region was associated with ciprofloxacin resistance for two A. butzleri and one A. cryaerophilus ciprofloxacin-resistant strains.
- Subjects :
- DNA, Bacterial
Microbiology (medical)
Arcobacter cryaerophilus
Helicobacter pullorum
Molecular Sequence Data
Immunology
Mutation, Missense
Sequence Homology
Biology
DNA, Ribosomal
Microbiology
DNA gyrase
03 medical and health sciences
Ciprofloxacin
Helicobacter
RNA, Ribosomal, 16S
Drug Resistance, Bacterial
Humans
Immunology and Allergy
Amino Acid Sequence
Phylogeny
030304 developmental biology
Antibacterial agent
Arcobacter
Genetics
0303 health sciences
Base Sequence
Phylogenetic tree
030306 microbiology
Nucleic acid sequence
Campylobacter
Sequence Analysis, DNA
General Medicine
biochemical phenomena, metabolism, and nutrition
16S ribosomal RNA
biology.organism_classification
Anti-Bacterial Agents
Wolinella
Arcobacter butzleri
Infectious Diseases
[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology
Amino Acid Substitution
DNA Gyrase
Gram-Negative Bacterial Infections
Sequence Alignment
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- FEMS Immunology & Medical Microbiology, FEMS Immunology & Medical Microbiology, 2007, 49 (3), pp.337-45. ⟨10.1111/j.1574-695X.2006.00208.x⟩
- Accession number :
- edsair.doi.dedup.....34ecb1c6c0ea6c6e7782ac934d7b789a