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Lung volume in mechanically ventilated patients: measurement by simplified helium dilution compared to quantitative CT scan
- Source :
- Intensive care medicine. 30(2)
- Publication Year :
- 2003
-
Abstract
- OBJECTIVE: We describe a simplified helium dilution technique to measure end-expiratory lung volume (EELV) in mechanically ventilated patients. We assessed both its accuracy in comparison with quantitative computerized tomography (CT) and its precision. DESIGN AND SETTING: Prospective human study. PATIENTS: Twenty-one mechanically ventilated ALI/ARDS patients. INTERVENTIONS: All patients underwent a spiral CT scan of the thorax during an end-expiratory occlusion. From the CT scan we computed the gas volume of the lungs (EELVCT).Within a few minutes, a rebreathing bag, containing a known amount of helium, was connected to the endotracheal tube, and the gas mixture diluted in the patient's lungs by delivering at least ten large tidal volumes. From the final helium concentration, EELV could be calculated by a standard formula (EELVHe). MEASUREMENT AND RESULTS: The results obtained by the two techniques showed a good correlation (EELVHe=208+0.858xEELV(CT), r=0.941; P
- Subjects :
- Thorax
Adult
Male
medicine.medical_treatment
Indicator Dilution Techniques
Critical Care and Intensive Care Medicine
Helium
Mechanical Ventilation, Acute Respiratory Failure, Computed Tomography, Lung Volumes
Mechanical ventilation
Functional residual capacity
Intensive care
End-expiratory lung volume
medicine
Humans
Lung volumes
Prospective Studies
MED/41 - ANESTESIOLOGIA
Computed tomography
Helium dilution
Aged
Respiratory Distress Syndrome
business.industry
Reproducibility of Results
respiratory system
Middle Aged
Respiration, Artificial
respiratory tract diseases
Dilution
Helium dilution technique
ARDS
Female
Tomography
Nuclear medicine
business
Lung Volume Measurements
Tomography, X-Ray Computed
Subjects
Details
- ISSN :
- 03424642
- Volume :
- 30
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Intensive care medicine
- Accession number :
- edsair.doi.dedup.....34c2aa7f61ff3f4469d405b37f278461