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Extra-weak chemiluminescence of drugs. XI. Quenching effects of purine and pyrimidine derivatives on the extra-weak chemiluminescence derived from the Maillard reaction
- Source :
- Journal of bioluminescence and chemiluminescence. 6(1)
- Publication Year :
- 1991
-
Abstract
- Quenching effects of purine and pyrimidine derivatives on the extra-weak chemiluminescence (CL) derived from the Maillard reaction of L-lysine with D-arabinose were investigated. The pyrimidine derivatives 2'-deoxy cytidine, uridine, and uracil quenched the CL. Cytidine did not quench the CL. Purine derivatives, e.g. uric acid and 1-methyl adenosine were particularly effective in quenching the CL. 5-Methyl adenine and xanthine also quenched the CL, but adenosine had no effect. A comparison of the CL-quenching abilities of compounds that have common basic structure was made; those with ribose at the 5-position were the strongest quenchers. A linear relationship between CL-quenching activity and the HOMO energy of the pi orbital for the various compounds was shown.
- Subjects :
- Purine
Pyrimidine
Lysine
Biophysics
Cytidine
Uracil
In Vitro Techniques
Xanthine
Photochemistry
Arabinose
Uridine
law.invention
chemistry.chemical_compound
Maillard reaction
symbols.namesake
Pyrimidines
chemistry
Chemistry (miscellaneous)
law
Purines
Luminescent Measurements
symbols
Thermodynamics
Chemiluminescence
Subjects
Details
- ISSN :
- 08843996
- Volume :
- 6
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Journal of bioluminescence and chemiluminescence
- Accession number :
- edsair.doi.dedup.....3494c3a5325f28db2bec9b2bcc6133cd