Net efflux rate of norepinephrine from platelets in DOCA- and salt-treated rats

39 Wistar Kyoto rats were treated for 4 weeks with weekly injections of DOCA and extra sodium chloride in drinking water. The efflux rate of norepinephrine from platelets (k) was determined in 13 samples, each consisting of pooled blood from 3 animals. The efflux rate of norepinephrine was significantly higher (k=24.7±4.9) in these animals than in the 29 controls in which 10 k-determinations were made (k=17.0±4.5) (p