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Diffuse Gallbladder Adenomyomatosis in a Child
- Source :
- Cureus
- Publication Year :
- 2021
- Publisher :
- Cureus, Inc., 2021.
-
Abstract
- Adenomyomatosis of the gallbladder is a benign condition, usually occurring in middle age, in which the epithelium of the gallbladder proliferates and the gallbladder wall thickens with the presence of Rokitansky-Aschoff sinuses (RAS). The diffuse form is an unusual subtype of adenomyomatosis. Herein, we describe a 17-year-old female who presented with dull and intermittent pain in the right hypochondriac region for more than a month. Ultrasound followed by magnetic resonance imaging showed marked diffuse gallbladder wall thickening. A gross cholecystectomy specimen showed a diffusely enlarged gallbladder. The final diagnosis of gallbladder adenomyomatosis (GA) was confirmed by the histopathologic appearance of muscular and epithelial hyperplasia, contributing to mural thickening with epithelial invaginations forming the pathognomonic intramural diverticula known as the RAS. This case highlights that the diffuse form of GA is uncommon and is often accompanied by chronic inflammation, sometimes requiring differential diagnosis from gallbladder malignancies, especially when there is no image showing a “comet tail” of cholesterol crystals in the wall.
- Subjects :
- Pathology
medicine.medical_specialty
Intermittent pain
medicine.medical_treatment
diffuse adenomyomatosis
030204 cardiovascular system & hematology
Pediatrics
03 medical and health sciences
0302 clinical medicine
children
Pathognomonic
medicine
magnetic resonance imaging
gallbladder
Adenomyomatosis
medicine.diagnostic_test
business.industry
Gallbladder
General Engineering
Invagination
Magnetic resonance imaging
ultrasonography
medicine.anatomical_structure
Cholecystectomy
Differential diagnosis
Radiology
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 21688184
- Database :
- OpenAIRE
- Journal :
- Cureus
- Accession number :
- edsair.doi.dedup.....343c918baf1339a3e564404f63ea1dd4