Back to Search
Start Over
Increased frequency of micronuclei in lymphocytes of Swedish chimney sweeps
- Source :
- International Archives of Occupational and Environmental Health. 66:185-187
- Publication Year :
- 1994
- Publisher :
- Springer Science and Business Media LLC, 1994.
-
Abstract
- Forty-five Swedish chimney sweeps and 49 controls were investigated with micronuclei stimulated by phytohemagglutinin and pokeweed mitogen and by analysis of lymphocyte subgroups and neutrophilic leukocytes. There was a statistically significant effect among sweeps with respect to both micronuclei variables and neutrophilic leukocytes. The effect on lymphocyte micronuclei was most prominent in pokeweed mitogen-stimulated cells, which may imply that the T4 lymphocytes were preferentially damaged by the occupational exposure.
- Subjects :
- Adult
Adolescent
Neutrophils
T-Lymphocytes
Lymphocyte
Mutagen
Biology
medicine.disease_cause
complex mixtures
chemistry.chemical_compound
Occupational Exposure
Benzo(a)pyrene
medicine
Humans
T4 Lymphocytes
Sweden
B-Lymphocytes
Micronucleus Tests
Pokeweed mitogen
Smoking
Public Health, Environmental and Occupational Health
Asbestos
Middle Aged
medicine.anatomical_structure
chemistry
Toxicity
Immunology
Micronucleus test
Occupational exposure
Subjects
Details
- ISSN :
- 14321246 and 03400131
- Volume :
- 66
- Database :
- OpenAIRE
- Journal :
- International Archives of Occupational and Environmental Health
- Accession number :
- edsair.doi.dedup.....3435bb34379bab1d944a330fc68fa969