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High-dose Radiotherapy or Androgen Deprivation Therapy (HEAT) as Treatment Intensification for Localized Prostate Cancer
- Source :
- European Urology, 82(1), 106-114. Elsevier, European urology, 82(1), 106-114. Elsevier
- Publication Year :
- 2022
-
Abstract
- Background: The relative benefits of radiotherapy (RT) dose escalation and the addition of short-term or long-term androgen deprivation therapy (STADT or LTADT) in the treatment of prostate cancer are unknown. Objective: To perform a network meta-analysis (NMA) of relevant randomized trials to compare the relative benefits of RT dose escalation ± STADT or LTADT. Design, setting, and participants: An NMA of individual patient data from 13 multicenter randomized trials was carried out for a total of 11 862 patients. Patients received one of the six permutations of low-dose RT (64 to
Details
- Language :
- English
- ISSN :
- 03022838
- Volume :
- 82
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- European urology
- Accession number :
- edsair.doi.dedup.....33f45f1d93c0238bd6e091ba39814978