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Epithelial ovarian cancer
- Source :
- Best practiceresearch. Clinical obstetricsgynaecology. 26(3)
- Publication Year :
- 2011
-
Abstract
- The incidence of epithelial ovarian cancer in women aged 40 years and younger is 3–17%. The management of these women is challenging and requires balancing the need to treat epithelial ovarian cancer adequately and preserving reproductive potential. Fertility-sparing surgery, especially for early stage epithelial ovarian cancer, seems to be associated with equivalent clinical and cancer outcomes while preserving reproductive potential. A complete staging and cytoreductive procedure retaining the uterus, and at least one grossly normal ovary, is the minimum recommended procedure. Adjuvant chemotherapy with a platinum-taxane combination is recommended as clinically indicated, and is associated with better cancer and survival outcomes. Adjuvant treatment does not seem to increase the risk of congenital anomalies in subsequent pregnancies. Targeted therapy and ovarian cryopreservation are largely experimental and cannot be recommended as part of the clinical standard of care.
- Subjects :
- Oncology
Infertility
medicine.medical_specialty
medicine.medical_treatment
Ovary
Carcinoma, Ovarian Epithelial
Targeted therapy
Internal medicine
medicine
Carcinoma
Humans
Ovarian tissue cryopreservation
Fertility preservation
Neoplasms, Glandular and Epithelial
Neoplasm Staging
Cryopreservation
Ovarian Neoplasms
Chemotherapy
business.industry
Obstetrics and Gynecology
Cancer
Fertility Preservation
General Medicine
medicine.disease
medicine.anatomical_structure
Chemotherapy, Adjuvant
Female
business
Infertility, Female
Organ Sparing Treatments
Subjects
Details
- ISSN :
- 15321932
- Volume :
- 26
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Best practiceresearch. Clinical obstetricsgynaecology
- Accession number :
- edsair.doi.dedup.....336e1b17f33baaf53c1f198637c1f5b4