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Pseudomonas aeruginosa Outbreak in a Neonatal Intensive Care Unit Attributed to Hospital Tap Water
- Source :
- Infection Control & Hospital Epidemiology. 38:801-808
- Publication Year :
- 2017
- Publisher :
- Cambridge University Press (CUP), 2017.
-
Abstract
- OBJECTIVETo investigate an outbreak of Pseudomonas aeruginosa infections and colonization in a neonatal intensive care unit.DESIGNInfection control assessment, environmental evaluation, and case-control study.SETTINGNewly built community-based hospital, 28-bed neonatal intensive care unit.PATIENTSNeonatal intensive care unit patients receiving care between June 1, 2013, and September 30, 2014.METHODSCase finding was performed through microbiology record review. Infection control observations, interviews, and environmental assessment were performed. A matched case-control study was conducted to identify risk factors for P. aeruginosa infection. Patient and environmental isolates were collected for pulsed-field gel electrophoresis to determine strain relatedness.RESULTSIn total, 31 cases were identified. Case clusters were temporally associated with absence of point-of-use filters on faucets in patient rooms. After adjusting for gestational age, case patients were more likely to have been in a room without a point-of-use filter (odds ratio [OR], 37.55; 95% confidence interval [CI], 7.16–∞). Case patients had higher odds of exposure to peripherally inserted central catheters (OR, 7.20; 95% CI, 1.75–37.30) and invasive ventilation (OR, 5.79; 95% CI, 1.39–30.62). Of 42 environmental samples, 28 (67%) grew P. aeruginosa. Isolates from the 2 most recent case patients were indistinguishable by pulsed-field gel electrophoresis from water-related samples obtained from these case-patient rooms.CONCLUSIONSThis outbreak was attributed to contaminated water. Interruption of the outbreak with point-of-use filters provided a short-term solution; however, eradication of P. aeruginosa in water and fixtures was necessary to protect patients. This outbreak highlights the importance of understanding the risks of stagnant water in healthcare facilities.Infect Control Hosp Epidemiol 2017;38:801–808
- Subjects :
- Male
0301 basic medicine
Microbiology (medical)
Catheterization, Central Venous
medicine.medical_specialty
Pediatrics
Neonatal intensive care unit
Epidemiology
030106 microbiology
Colony Count, Microbial
medicine.disease_cause
Disease Outbreaks
03 medical and health sciences
0302 clinical medicine
Risk Factors
Intensive Care Units, Neonatal
Health care
medicine
Humans
Infection control
Pseudomonas Infections
030212 general & internal medicine
business.industry
Pseudomonas aeruginosa
Drinking Water
Micropore Filters
Infant, Newborn
Case-control study
Infant
Outbreak
Gestational age
Odds ratio
Respiration, Artificial
Electrophoresis, Gel, Pulsed-Field
Infectious Diseases
Case-Control Studies
Emergency medicine
Female
Sanitary Engineering
business
Subjects
Details
- ISSN :
- 15596834 and 0899823X
- Volume :
- 38
- Database :
- OpenAIRE
- Journal :
- Infection Control & Hospital Epidemiology
- Accession number :
- edsair.doi.dedup.....33342925791d306a8ab12ad79e6e2434