Supplemental Figures from TALEN-Mediated Inactivation of PD-1 in Tumor-Reactive Lymphocytes Promotes Intratumoral T-cell Persistence and Rejection of Established Tumors

PD-1-TALEN activity screen in murine thymoma EL4 cells.PD-1 gene inactivation in pmel-1 CD8+T cells and functional analysis. PD-1-TALEN activity in TRL from MCA205. Effector/memory phenotype of TRL from MCA205.