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Increased risk of stroke after septicaemia: a population-based longitudinal study in Taiwan
- Source :
- PLoS ONE, Vol 9, Iss 2, p e89386 (2014), PLoS ONE
- Publication Year :
- 2014
- Publisher :
- Public Library of Science (PLoS), 2014.
-
Abstract
- Inflammation and infection have been noted to increase stroke risk. However, the association between septicaemia and increased risk of stroke remains unclear. This population-based cohort study, using a National Health Insurance database, aimed to investigate whether patients with septicaemia are predisposed to increased stroke risk. The study included all patients hospitalised for septicaemia for the first time between 2000 and 2003 without prior stroke. Patients were followed until the end of 2010 to evaluate incidence of stroke. An age-, gender- and co-morbidities-matched cohort without prior stroke served as the control. Cox's proportional hazards regressions were used to assess differences in stroke risk between groups. Based on hazard ratios (HRs), patients with septicaemia had greater stroke risk, especially in the younger age groups (age 0.05). Haemorrhagic stroke was the dominant type (ischaemic stroke: HR = 1.20, 95% CI: 1.06-1.37, p
- Subjects :
- Male
Bacterial Diseases
Pediatrics
Longitudinal study
Critical Care and Emergency Medicine
Databases, Factual
Epidemiology
Myocardial Ischemia
lcsh:Medicine
Comorbidity
Cardiovascular
Atrial Fibrillation
Clinical Epidemiology
Longitudinal Studies
lcsh:Science
Stroke
Aged, 80 and over
education.field_of_study
Multidisciplinary
Incidence
Incidence (epidemiology)
Hazard ratio
Age Factors
Atrial fibrillation
Middle Aged
Hemorrhagic Stroke
Infectious Diseases
Neurology
Nephrology
Hypertension
Cohort
Medicine
Female
Research Article
Cohort study
Adult
Risk
medicine.medical_specialty
Clinical Research Design
Cerebrovascular Diseases
Population
Taiwan
Sepsis
Diabetes Mellitus
medicine
Humans
cardiovascular diseases
education
Aged
Ischemic Stroke
business.industry
lcsh:R
medicine.disease
lcsh:Q
business
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 9
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....32f2d367132eb15613dabed4111313d0