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Quality of Life and Sexual Functioning in Cervical Cancer Survivors
- Source :
- Journal of Clinical Oncology. 23:7428-7436
- Publication Year :
- 2005
- Publisher :
- American Society of Clinical Oncology (ASCO), 2005.
-
Abstract
- Purpose To compare quality of life and sexual functioning in cervical cancer survivors treated with either radical hysterectomy and lymph node dissection or radiotherapy. Methods Women were interviewed at least 5 years after initial treatment for cervical cancer. Eligible women had squamous cell tumors smaller than 6 cm at diagnosis, were currently disease-free, and had either undergone surgery or radiotherapy, but not both. The two treatment groups were then compared using univariate analysis and multivariate linear regression with a control group of age- and race-matched women with no history of cancer. Results One hundred fourteen patients (37 surgery, 37 radiotherapy, 40 controls) were included for analysis. When compared with surgery patients and controls using univariate analysis, radiation patients had significantly poorer scores on standardized questionnaires measuring health-related quality of life (physical and mental health), psychosocial distress and sexual functioning. The disparity in sexual function remained significant in a multivariate analysis. Univariate and multivariate analyses did not show significant differences between radical hysterectomy patients and controls on any of the outcome measures. Conclusion Cervical cancer survivors treated with radiotherapy had worse sexual functioning than did those treated with radical hysterectomy and lymph node dissection. In contrast, these data suggest that cervical cancer survivors treated with surgery alone can expect overall quality of life and sexual function not unlike that of peers without a history of cancer.
- Subjects :
- Adult
Cancer Research
medicine.medical_specialty
Sexual Behavior
medicine.medical_treatment
Uterine Cervical Neoplasms
Adenocarcinoma
Hysterectomy
Carcinoma, Adenosquamous
Quality of life
Surveys and Questionnaires
Internal medicine
Adaptation, Psychological
medicine
Humans
Survivors
Cervical cancer
Univariate analysis
business.industry
Cancer
Middle Aged
medicine.disease
Surgery
Radiation therapy
Distress
Oncology
Case-Control Studies
Carcinoma, Squamous Cell
Quality of Life
Female
business
Psychosocial
Subjects
Details
- ISSN :
- 15277755 and 0732183X
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Oncology
- Accession number :
- edsair.doi.dedup.....32b65e1b527560c50c840ef4ede661ec