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Decreased uric acid levels in the acute phase of Plasmodium vivax malaria
- Source :
- Revista da Sociedade Brasileira de Medicina Tropical, Vol 52, Iss 0 (2019), Revista da Sociedade Brasileira de Medicina Tropical, Volume: 52, Article number: e20170412, Published: 16 MAY 2019
- Publication Year :
- 2019
- Publisher :
- FapUNIFESP (SciELO), 2019.
-
Abstract
- INTRODUCTION Uric acid is one of the compounds associated with the inflammatory process in malaria. It acts as an indicator of cellular damage by activating the immune response and inflammatory process. METHODS: We measured serum concentrations of uric acid in 60 symptomatic patients before and after treatment for malarial infections caused by Plasmodium vivax. RESULTS: Lower serum concentrations of uric acid were found during the acute phase of P. vivax malaria compared to those in its convalescent phase (p < 0.0001). CONCLUSIONS: Patients in the acute phase of malaria had lower uric acid levels than those in its convalescent phase.
- Subjects :
- Adult
Male
0301 basic medicine
Microbiology (medical)
lcsh:Arctic medicine. Tropical medicine
Adolescent
lcsh:RC955-962
030106 microbiology
030231 tropical medicine
Plasmodium vivax
Convalescent phase
Antimalarials
Young Adult
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Immune system
parasitic diseases
Malaria, Vivax
Humans
Medicine
Child
Acute phase
Aged
biology
business.industry
Middle Aged
biology.organism_classification
medicine.disease
Malaria
Infectious Diseases
chemistry
Child, Preschool
Acute Disease
Immunology
Vivax malaria
Uric acid
Female
Parasitology
Plasmodium vivax Malaria
business
Biomarkers
After treatment
Subjects
Details
- ISSN :
- 16789849 and 00378682
- Volume :
- 52
- Database :
- OpenAIRE
- Journal :
- Revista da Sociedade Brasileira de Medicina Tropical
- Accession number :
- edsair.doi.dedup.....32b0551f68f82d384c33548f18aec85a