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Application of CT-PSF-based computer-simulated lung nodules for evaluating the accuracy of computer-aided volumetry
- Source :
- Radiological physics and technology. 5(2)
- Publication Year :
- 2011
-
Abstract
- With the wide dissemination of computed tomography (CT) screening for lung cancer, measuring the nodule volume accurately with computer-aided volumetry software is increasingly important. Many studies for determining the accuracy of volumetry software have been performed using a phantom with artificial nodules. These phantom studies are limited, however, in their ability to reproduce the nodules both accurately and in the variety of sizes and densities required. Therefore, we propose a new approach of using computer-simulated nodules based on the point spread function measured in a CT system. The validity of the proposed method was confirmed by the excellent agreement obtained between computer-simulated nodules and phantom nodules regarding the volume measurements. A practical clinical evaluation of the accuracy of volumetry software was achieved by adding simulated nodules onto clinical lung images, including noise and artifacts. The tested volumetry software was revealed to be accurate within an error of 20 % for nodules >5 mm and with the difference between nodule density and background (lung) (CT value) being 400–600 HU. Such a detailed analysis can provide clinically useful information on the use of volumetry software in CT screening for lung cancer. We concluded that the proposed method is effective for evaluating the performance of computer-aided volumetry software.
- Subjects :
- Lung Neoplasms
Physical Therapy, Sports Therapy and Rehabilitation
Image processing
Sensitivity and Specificity
Imaging phantom
Software
medicine
Image Processing, Computer-Assisted
Radiology, Nuclear Medicine and imaging
Computer Simulation
Radiation
Lung
business.industry
Phantoms, Imaging
Nodule (medicine)
General Medicine
Tumor Burden
Ct screening
medicine.anatomical_structure
Computer-aided
Tomography
medicine.symptom
business
Nuclear medicine
Tomography, X-Ray Computed
Subjects
Details
- ISSN :
- 18650341
- Volume :
- 5
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Radiological physics and technology
- Accession number :
- edsair.doi.dedup.....328287812d119e20ca70a7c266da9c25