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Can virostatic chemotherapy and/or adoptive allogeneic immunotherapy eradicate in vivo Friend's virus infection?

Authors :
E. Chenu
C. Bourut
Mathé G
M Trabaud
Source :
Biomedicine & Pharmacotherapy. 44:57-59
Publication Year :
1990
Publisher :
Elsevier BV, 1990.

Abstract

While none of the three drugs which exert an in vitro anti-HIV effect, neither AZT nor the other two. acriflavine and elliptinium, which we have shown to be more efficient than AZT, is able to eradicate Friend's virus in vivo , the combination of the 3 drugs at much smaller doses than when given alone seems able to eradicate it in almost 30% of the infected animals. This possible eradicatng effect of virostatics in combination is compared with the results we had previously obtained with lymphocytes of virus-immunized allogeneic donors. Friend's virus / virostatic chemotherapy / adoptive allogeneic Immunotherapy.

Details

ISSN :
07533322
Volume :
44
Database :
OpenAIRE
Journal :
Biomedicine & Pharmacotherapy
Accession number :
edsair.doi.dedup.....3207b5d42e244936dc311b47a95e4fe5
Full Text :
https://doi.org/10.1016/0753-3322(90)90071-g