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Can virostatic chemotherapy and/or adoptive allogeneic immunotherapy eradicate in vivo Friend's virus infection?
- Source :
- Biomedicine & Pharmacotherapy. 44:57-59
- Publication Year :
- 1990
- Publisher :
- Elsevier BV, 1990.
-
Abstract
- While none of the three drugs which exert an in vitro anti-HIV effect, neither AZT nor the other two. acriflavine and elliptinium, which we have shown to be more efficient than AZT, is able to eradicate Friend's virus in vivo , the combination of the 3 drugs at much smaller doses than when given alone seems able to eradicate it in almost 30% of the infected animals. This possible eradicatng effect of virostatics in combination is compared with the results we had previously obtained with lymphocytes of virus-immunized allogeneic donors. Friend's virus / virostatic chemotherapy / adoptive allogeneic Immunotherapy.
- Subjects :
- viruses
medicine.medical_treatment
Biology
Virus
Mice
chemistry.chemical_compound
Drug Therapy
In vivo
hemic and lymphatic diseases
medicine
Animals
Pharmacology
Elliptinium
Chemotherapy
Leukemia, Experimental
General Medicine
Immunotherapy
Virology
In vitro
Drug Combinations
chemistry
Immunology
HIV-1
Acriflavine
Zidovudine
Subjects
Details
- ISSN :
- 07533322
- Volume :
- 44
- Database :
- OpenAIRE
- Journal :
- Biomedicine & Pharmacotherapy
- Accession number :
- edsair.doi.dedup.....3207b5d42e244936dc311b47a95e4fe5
- Full Text :
- https://doi.org/10.1016/0753-3322(90)90071-g