Zinc sulphate reduces activity-stress gastric lesions in rats

1. 1. Daily i.p. injections of zinc sulphate significantly reduced the frequency and severity of activity-stress gastric lesions in rats in a dose-related fashion. 2. 2. These lesions are believed to be of a non-acid etiology and respond primarily to centrally-acting agents. 3. 3. The present results suggest that some local factors contribute to activity-stress gastric damage.