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Fish/shellfish intake and the risk of head and neck cancer
- Source :
- European Journal of Cancer Prevention. 28:102-108
- Publication Year :
- 2019
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2019.
-
Abstract
- Fish intake and other dietary sources of omega-3 fatty acids have been shown to be associated with a reduced risk for some cancers. Although previous studies of head and neck cancer have reported associations with different dietary factors, including reduced risks for fruits and vegetables and putatively healthy dietary patterns, associations specific to fish intake are unclear. This study investigated the association between fish/shellfish intake and risk of squamous cell carcinoma of the head and neck (SCCHN) using data from the Carolina Head and Neck Cancer Epidemiology Study, a population-based case-control study conducted in 46 North Carolina counties with cases recruited from 2002 through 2006. Controls were frequency matched to the cases on age, sex, and race; the final sample size was 1039 cases and 1375 controls. Demographic, lifestyle, and dietary information were collected using an in-person interviewer-administered structured questionnaire. Multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were estimated with unconditional logistic regression. Patients whose fish/shellfish intake was among the highest tertile had a 20% lower odds of SCCHN compared with those in the lowest tertile (OR: 0.80; 95% CI: 0.60-1.07) after adjustment for the matching and other factors (income, energy intake, fruit intake, cigarette smoking, and alcohol intake). The inverse association was more pronounced for oral cavity and oropharyngeal tumors, for African Americans, and for females, but CIs were wide. To further investigate this potential risk reduction strategy for SCCHN, future studies should consider examining specific fish/shellfish, cooking practices, and other omega-3 fatty acid sources.
- Subjects :
- Adult
Male
Cancer Research
medicine.medical_specialty
Epidemiology
Population
Logistic regression
Article
Young Adult
03 medical and health sciences
0302 clinical medicine
Risk Factors
Environmental health
North Carolina
medicine
Animals
Humans
030212 general & internal medicine
Young adult
education
Aged
Shellfish
Aged, 80 and over
education.field_of_study
business.industry
Head and neck cancer
Fishes
Public Health, Environmental and Occupational Health
Case-control study
Odds ratio
Middle Aged
Prognosis
medicine.disease
Confidence interval
Diet
Oncology
Head and Neck Neoplasms
Case-Control Studies
030220 oncology & carcinogenesis
Carcinoma, Squamous Cell
Female
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 09598278
- Volume :
- 28
- Database :
- OpenAIRE
- Journal :
- European Journal of Cancer Prevention
- Accession number :
- edsair.doi.dedup.....31f74f321d82ed7aeb80ef8ea22d0c43