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Ocular manifestations of Noonan syndrome in twin siblings: a case report of keratoconus with acute corneal hydrops
- Source :
- Indian Journal of Ophthalmology, Indian Journal of Ophthalmology, Vol 62, Iss 12, Pp 1171-1173 (2014)
- Publication Year :
- 2015
-
Abstract
- Ocular manifestations of Noonan syndrome (NS) in a set of healthy 20-year-old African-American fraternal twins are reported with emphasis on a rare finding of keratoconus with acute corneal hydrops in one twin. Both the twins had learning disabilities and attended a special needs school. Evaluation included visual acuity assessment, tonometry and external eye, slit lamp and dilated fundus examinations, topography with Pentacam and external photographs. The first case was more remarkable as keratoconus with acute corneal hydrops was observed. The patient presented with severe cloudy vision that had worsened over a span of 1 month. It improved significantly on follow-up. The second case included a unique constellation of ocular pathology that highlights the diversity of NS manifestations even amongst twins. Conservative treatment of keratoconus with acute corneal hydrops in a NS patient helped largely resolve the patient's condition. We report the diverse spectrum of ocular manifestations associated with this rare congenital disorder.
- Subjects :
- Malignant glaucoma
Visual acuity
genetic structures
Ocular Pathology
Visual Acuity
myopic shift
Fundus (eye)
Levodopa
Cornea
lcsh:Ophthalmology
pharmacoeconomics
pseudophakic
hydrophobic acrylic intraocular lens
refractive error
colistin
Low vision
Children
Anterior chamber
occlusion amblyopia
Acute corneal hydrops
pseudopapilloedema
medicine.diagnostic_test
External limiting membrane
intraocular parasite
Corneal Edema
Noonan Syndrome
transient myopia
Corneal topography
Acute angle closure glaucoma
Automated retinal imaging
diabetic retinopathy
endophthalmitis
ERG
Optic nerve head drusen
Pseudomonas aeruginosa
Acute Disease
Acute retinal pigment epithelitis
Female
medicine.symptom
Corneal hydrops
polymethyl methacrylate
SD-OCT
Keratoconus
medicine.medical_specialty
zonulo-hyaloido-vitrectomy
oseltamivir
keratoconus
vitrectomy
surgical management
Brief Communication
Cataract
Young Adult
intraocular lens implantation
Ophthalmology
medicine
Diseases in Twins
Humans
Carbonic anhydrase inhibitor
low vision aids
optical coherence tomography
business.industry
screening
subluxated lens
Danon disease
Siblings
ciliochoroidal effusion
Corneal Topography
papilledema
medicine.disease
eye diseases
macular hole
glaucoma
predictors
Crowding
quality of life
congenital cataract
lcsh:RE1-994
Noonan syndrome
Cost-effectiveness
reverse amblyopia
multifocal electroretinogram
retinal disease
sense organs
logMAR chart
business
Linguatula serrata (tongue worm)
Congenital disorder
Subjects
Details
- ISSN :
- 19983689
- Volume :
- 62
- Issue :
- 12
- Database :
- OpenAIRE
- Journal :
- Indian journal of ophthalmology
- Accession number :
- edsair.doi.dedup.....31982f938bed5f64eb7c30e57d42ecac