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Functional Analysis Using Whole-Genome Sequencing of a Drug-Sensitive Mycobacterium tuberculosis Strain from Peru

Authors :
Victor Borda
Heinner Guio
David Tarazona
J. C. Agapito
M. Galarza
Source :
Genome Announcements
Publication Year :
2014
Publisher :
American Society for Microbiology, 2014.

Abstract

We report the whole-genome sequence of a Latin American-Mediterranean (LAM) lineage drug-sensitive Mycobacterium tuberculosis strain from Peru, INS-SEN. The functional analysis revealed more mutations in secondary metabolite biosynthesis, transport, and catabolism (clusters of orthologous groups [COG] category Q) than for other LAM-sensitive strains. This study contributes to the understanding of the genomic diversity of drug-sensitive M. tuberculosis .

Details

ISSN :
21698287
Volume :
2
Database :
OpenAIRE
Journal :
Genome Announcements
Accession number :
edsair.doi.dedup.....31769a199551ea4ff27ecbaaa357a942