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International Variability in the Reimbursement of Cancer Drugs by Publically Funded Drug Programs

Authors :
Parneet Cheema
Maureen E. Trudeau
M. Migus
Brian Godman
Scott Gavura
Lyndee Yeung
Source :
Current Oncology, Volume 19, Issue 3, Pages 946-176
Publication Year :
2012
Publisher :
MDPI AG, 2012.

Abstract

Evaluate inter-country variability in the reimbursement of publically funded cancer drugs, and identify factors such as cost containment measures that may contribute to variability. As of February 28, 2010, licensed indications for 10 cancer drugs (bevacizumab, bortezomib, cetuximab, erlotinib, imatinib, pemetrexed, rituximab, sorafenib, sunitinib, and trastuzumab) were obtained from the drug registries of 6 licensing authorities corresponding to 13 countries or regions: Australia, Canada (Ontario), England, Finland, France, Italy, Germany, Japan, New Zealand, the Netherlands, Scotland, Sweden, and the United States (Medicare Parts B and D). Number of licensed indications reimbursed by public payers and the use of cost containment measures were obtained by survey of health authorities involved in reimbursement and through public documents. The 48 identified licensed indications varied between agencies (range: 36&ndash<br />44 indications). Finland, France, Germany, Sweden, and the United States reimbursed the highest percentage of indications (range: 90%&ndash<br />100%). Canada (54%), Australia (46%), Scotland (40%), England (38%), and New Zealand (25%) reimbursed the least. All 5 countries with the lowest rate of reimbursement incorporated a cost-effectiveness analysis into reimbursement decisions and rejected submissions for reimbursement mainly because of lack of cost effectiveness<br />in New Zealand, lack of cost effectiveness was the second leading cause of rejection after excessive cost. In 9 countries, risk-sharing agreements were used to contain costs. Indications initially not recommended for reimbursement (9 in Australia, 5 in Canada, and 3 in England, New Zealand, and Scotland) were subsequently approved with risk-sharing agreements or special pricing arrangements. Reimbursement of publically funded cancer drugs varies globally. The cause is multifactorial.

Details

ISSN :
17187729
Volume :
19
Database :
OpenAIRE
Journal :
Current Oncology
Accession number :
edsair.doi.dedup.....3144b69827f7a37c87b758f2d9a94e67
Full Text :
https://doi.org/10.3747/co.19.946