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Evaluation of visual pathways using visual evoked potentials in the patients with impaired fasting glucose and impaired glucose tolerance
- Source :
- The International journal of neuroscience. 129(1)
- Publication Year :
- 2018
-
Abstract
- There are many studies on degeneration of the ganglion cells using visual evoked potential (VEP) in Diabetes mellitus (DM). The present study intended to investigate whether the retinopathy findings would be helpful for detecting the degeneration to develop or not in retinal ganglion cells with the VEP test before being detectable in ophthalmoscopic examination on prediabetic patients.The present study was conducted prospectively after obtaining approval from the Ethics Committee. In our study, the subjects were divided into three groups as impaired fasting glucose (IFG), impaired glucose tolerance (IGT) and normal patients. They also underwent physical, ophthalmological and VEP examination. Three main components of VEP obtained from these groups were N75, P100, and N145 latency and N75-P100 amplitude.The study participants consisted of the IFG group (n: 30, female/male ratio: 21/9; mean age: 49.17 ± 10.52 years), the IGT group (n: 30, female/male ratio: 23/7; mean age: 47.00 ± 11.09 years), and the Control Group (n: 40, female/male ratio: 30/10; mean age: 48.03 ± 10.96 years). Difference in sex and age between the study groups (p 0.05). P100 latency was found to increase significantly in comparison between the IGT and Control Group for both eyes (p right: 0.003, p left: 0.001) whereas it did not increase significantly in the comparison between the IFG and the Control Group (p right: 0.065, p left: 0.116).It was observed that VEP may be a parameter of predictive value that might be used in evaluating prediabetic cases in terms of retinopathies similar to DM.
- Subjects :
- 0301 basic medicine
Adult
Blood Glucose
Male
medicine.medical_specialty
genetic structures
Visual Acuity
Degeneration (medical)
Visual system
Impaired glucose tolerance
03 medical and health sciences
0302 clinical medicine
Internal medicine
Diabetes mellitus
Glucose Intolerance
medicine
Humans
Visual Pathways
Prospective Studies
Evoked potential
business.industry
General Neuroscience
General Medicine
Fasting
Middle Aged
medicine.disease
Impaired fasting glucose
Ganglion
030104 developmental biology
Endocrinology
medicine.anatomical_structure
Evoked Potentials, Visual
Female
business
030217 neurology & neurosurgery
Retinopathy
Subjects
Details
- ISSN :
- 15635279
- Volume :
- 129
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- The International journal of neuroscience
- Accession number :
- edsair.doi.dedup.....3143b0254dc1b8f81d91eec6b12eabc1