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The assessment of cardiac function with tissue Doppler imaging in fetuses with congenital diaphragmatic hernia
- Source :
- The Journal of Maternal-Fetal & Neonatal Medicine. 33:1233-1238
- Publication Year :
- 2019
- Publisher :
- Informa UK Limited, 2019.
-
Abstract
- Introduction: This study aimed to evaluate the cardiac function of fetuses with congenital diaphragmatic hernia by conventional echocardiography and spectral tissue Doppler imaging (s-TDI) and to evaluate the relationship between cardiac function and the severity of pulmonary hypoplasia. We also aimed to investigate the effect of diaphragmatic hernia side on fetal cardiac function. Methods: Fetal cardiac function were evaluated in 28 fetuses (20 with left-sided and 8 with right-sided) complicated with isolated congenital diaphragmatic hernia (CDH) and 56 gestational age matched control in this single center prospective study. s-TDI measurements were obtained at the right atrioventricular valve annulus. The annular peak velocities and their ratios, the time periods of cardiac cycle and myocardial performance index were calculated. Results: In comparison to controls, significantly prolonged isovolumetric contraction time (ICT ') and isovolumetric relaxation time (IRT ') and, significantly shortened ejection time (ET ') were observed in fetuses with CDH by s-TDI. Fetuses with CDH also had higher myocardial performance index (MPI ') z-scores compared to controls. There were no significant differences in terms of s-TDI cardiac function parameters between fetuses with right- and left-sided CDH. In correlation analysis, a significant positive correlation was found between ET ' value and o/e LHR. Conclusion: The signs of both systolic and diastolic altered function were observed in fetuses with CDH with s-TDI independent of the side of the hernia, and a significant positive correlation was observed between fetal cardiac systolic function and the severity of pulmonary hypoplasia.
- Subjects :
- Adult
Lung Diseases
Cardiac function curve
medicine.medical_specialty
Pulmonary Hypoplasia
Diastole
Ultrasonography, Prenatal
Young Adult
03 medical and health sciences
Pulmonary hypoplasia
0302 clinical medicine
Pregnancy
030225 pediatrics
Internal medicine
medicine
Humans
Abnormalities, Multiple
Diaphragmatic hernia
Hernia
Prospective Studies
Lung
Isovolumetric contraction
Echocardiography, Doppler, Pulsed
Global Cardiac Function
030219 obstetrics & reproductive medicine
Cardiac cycle
business.industry
Spectral Tissue Doppler İmaging
Obstetrics and Gynecology
Congenital diaphragmatic hernia
medicine.disease
Fetal Cardiac Dysfunction
Case-Control Studies
Fetal Cardiac Function
Pediatrics, Perinatology and Child Health
cardiovascular system
Cardiology
Female
Hernias, Diaphragmatic, Congenital
business
Spectral Tissue Doppler Imaging
Congenital Diaphragmatic Hernia
Subjects
Details
- ISSN :
- 14764954 and 14767058
- Volume :
- 33
- Database :
- OpenAIRE
- Journal :
- The Journal of Maternal-Fetal & Neonatal Medicine
- Accession number :
- edsair.doi.dedup.....31319168d6bc9d234aa5f7665047e131
- Full Text :
- https://doi.org/10.1080/14767058.2019.1674806